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Particle-enhanced optical immunoassays, including turbidimetry and nephelometry, remain attractive because they can provide rapid, homogeneous assay formats with relatively simple workflows. Turbidimetry offers the simplest optical implementation, while nephelometry can provide a more direct measurement of scattered light and may offer advantages where sensitivity, precision or background rejection are limiting.

In this article, Nick Collier, CTO Sagentia Medical, assesses those limits and suggests how they might be addressed.

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The highs and lows of turbidimetry and nephelometry for point of care immunoassays

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